Conference Programme

Wednesday, October 6, 2010

09:00 Registration

11:00 WELCOME & OPENING REMARKS

11:00 SCI-DSM Awards & Fellowship Ceremony

Prof. Gianluca Giorgi (President of the Mass Spectrometry Division of the Italian Chemical Society)

Prof.ssa Luisa Mosti (Past President of the Medicinal Chemistry Division of the Italian Chemical Society)

Dr. Giovanni Boccardi (AFI representative)

Welcome by Academic Authorities of the University of Milan

Chairperson: Gianluca Giorgi

12:00 Opening lecture: La Chimica nella creazione, nella conservazione e nel degrado dei beni artistici policromi Paolo Cremonesi, Centro per lo Studio dei Materiali per il Restauro,  Padova, (Italy)

12:45-14:30 Buffet Lunch

Afternoon Session

Chairpersons: Andrea Raffaelli and Emanuele Magi

14:30 We-Pl-01: Some thoughts on the electrospray ionization mechanisms Pietro Traldi, Consiglio Nazionale delle Ricerche, Institute of Molecular Science and Technologies (ISTM), Padova (Italy)

15:20 We-Or-01: Characterization of a new tripodal quinoline-8-olate gadolinium complex by infrared multiphoton dissociation and fourier-transform ion cyclotron resonance mass spectrometry Giuliana Bianco, University of Basilicata, Potenza (Italy)

15:40 We-Or-02: IRMPD spectroscopy - mass spectrometry of ionized amino acids: cysteine radical cation Simonetta Fornarini, University of Rome “La Sapienza”, (Italy)

16:00-16:30 Coffee Break

Chairpersons: Marica Orioli and Elisa Giocaliere

16:30 We-Or-03: Reactive landing of redox molecules onto electrodic surfaces: a new tool for biosensors development? Alessandra Tata (DSM award winner), University of Rome “La Sapienza”, (Italy)

16:50 We-Or-04: Small molecules analysis with high level of confidence Elisa Basso, Bruker Daltonics S.r.l., Macerata (Italy)

17:10 We-Or-05: New insight on the sodium bis(2-ethylhexyl) sulfosuccinate (AOT) charged supramolecular aggregates David Bongiorno, University of Palermo (Italy)

17:30 Poster Session and vendor exhibition

17:30 Meeting of the members of the Mass Spectrometry Division

19:00 Welcome cocktail

Thursday, October 7, 2010

Morning Session

Chairpersons: Giovanni Sindona and Fulvio Magni

09:00 Th-Pl-01: Using ion mobility spectrometry-mass spectrometry to unravel biomolecular assembly pathways Alison E Ashcroft, The Astbury Centre for Structural Molecular Biology, University of Leeds (UK)

09:50 Th-Or-01: Tissue protein profile of clear cell RCC by 2D-DIGE and MS: a proteomic glimpse of functional and network signatures Clizia Chinello, University of Milano-Bicocca, Monza (Italy)

10:10 Th-Or-02: Detergent enhancement of on-tissue protein signals for imaging studies using MALDI MS Veronica Mainini, University of Milano-Bicocca, Monza (Italy)

10:30 Th-Or-03: Investigation of the cutaneous proteome in humans: imaging MS of biopsies from skin ulcer Domenico Taverna, University of Calabria (Italy)

10:50-11:20 Coffee Break

Chairpersons: Donatella Caruso and Ornella Curcuruto

11:20 Th-Or-04: The potential of on-line HPLC-IMS-MS for qualitative and quantitative protein profiling in complex biological samples Mark McDowall, Waters MS Technologies Centre, Manchester (UK)

11:40 Th-Or-05: Analysis of cocaine, amphetamine, morphine, methadone and buprenorphine in human urine and hair by LC-HESI-triple quadrupole mass spectrometry Maura Brambilla, University Department of Laboratory Medicine, Hospital of Desio (Italy)

12:00 Th-Or-06: Development of a LC-MS/MS method for therapeutic drug monitoring of antidepressants and antipsychotics Sara Baldelli, Luigi Sacco University Hospital – University of Milan (Italy)

12:20 Th-Or-07: Large serum steroid profiling by isotopic dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS): comparison with routine immunoassays and reference intervals in adult population Flaminia Fanelli, S.Orsola-Malpighi Hospital, University of Bologna (Italy)

12:40-14:00 Buffet Lunch

14:00-15:30 Poster Session and vendor exhibition

Afternoon Session

Chairpersons: Marina Carini and Vincenzo Cunsolo

15:30 Th-Pl-02: Protein self-assembly in spider silk and design of artificial silk from recombinant proteins Jan Johansson, The Biomedical Centre, Uppsala (Sweden)

16:20 Th-Or-08: Analysis of soluble olfactory proteins through an integrated mass spectrometry approach Francesca Dani, University of Florence (Italy)

16:40 Th-Or-09: Covalent modifications of albumin cys34 as biomarker of mild oxidative stress Luca Regazzoni, University of Milan (Italy)

17:00-17:20 Coffee Break

17:20 Th-Or-10: Using MPS2 robotic system-LC-triple quadrupole MS for a fully automation, fast quantitation of immunosuppressant in blood Eligio Sebastiani, SRA Instruments (Italy)

17:40 Th-Or-11: Exploring the interactions of a “rule-breaker” iodo-platinum(II) complex with cytochrome C by mass spectrometry Elena Michelucci, University of Florence (Italy)

18:00 Th-Or-12:Urinary biomarkers of oxidative damage to guanine in oncologic patients receiving platinum based chemotherapy Roberta Andreoli, University of Parma (Italy)

18:20 End of session

20:30 CONFERENCE SOCIAL DINNER at Fonderia Napoleonica Eugenia

Friday, October 8, 2010

MS-Pharmaday

Morning Session

Chairpersons: Gabriella Massolini and Giancarlo Aldini

09:00 Fr-Pl-01: The application of mass spectrometry in the protection of intellectual property Christine Eckers, GlaxoSmithKline, Stevenage (UK)

09:50 Fr-Or-01: Development of receptor-based stationary phases for frontal affinity chromatography-mass spectrometry studies Caterina Temporini, University of Pavia (Italy)

10:10 Fr-Or-02: Setup of a flow injection method for the study of non covalent interaction on biopolymers Federico Riccardi Sirtori, Nerviano Medical Sciences – University of Milan (Italy)

10:30-11:00 Coffee Break

Chairpersons: Chiara Bigogno and Massimo Dondio

11:00 Fr-Or-03: Take full advantage of the increased capabilities of the current generation of hybrid FT mass spectrometers for protein analysis Giorgio Vago, Thermo Scientific (Italy)

11:20 Fr-Kl-01: I principi di buona pratica di laboratorio nella ricerca e nell'impiego dei metodi analitici Sergio Caroli, Istituto Superiore di Sanità, Rome (Italy)

12:00 Fr-Kl-02: Valutazione di casi di non conformità nell’impiego di metodi analitici in ambito BPL/GLP Enrico Invernizzi, Merck Serono, Ivrea (Italy)

12:40 Discussion

13:00-14:30 Buffet Lunch

Afternoon Session

Chairpersons: Maristella Colombo and Silvia Catinella

14:30 Fr-Or-04: The new high sensitivity triple quadrupole and its role within the pharmaceutical industry Victoria Starkie, Agilent Technologies Ltd (UK)

14:50 Fr-Or-05: Detection of hazelnut oil in virgin olive oil by analysis of their lipid and protein fraction by MALDI-TOF mass spectrometry Cosima Damiana Calvano, University of Bari (Italy)

15:10 Fr-Or-06: Novel invadopodia components revealed by differential proteomic analysis Francesca Attanasio, Consorzio Mario Negri Sud, S. Maria Imbaro, Chieti (Italy)

15:30 Fr-Or-07: LC-MS and LC-HRMS/MS studies of impurities in pharmaceutical industrial bulk of ketoprofen ethyl ester Fabiana Tavani, University of Florence (Italy)

15:50 Fr-Or-08: Mesoionic derivative of vanilmandelic acid: a serendipitous discovery with interesting applications Carlo Scapolla, University of Genoa (Italy)

16:10 Best Posters' Awards and Closure Remarks

16:40 Arrivederci